Marton P F
Scand J Haematol Suppl. 1975;23:27-48. doi: 10.1111/j.1600-0609.1975.tb01096.x.
Intracellular transport and storage of iron in bone marrow reticulum cells can be studied in the electron microscope by the recognition of iron macromolecules. Following artificially increased bone marrow erythrophagocytosis ferritin molecules accumulate both in the cell sap and in the lysosomes of erythroclastic reticulum cells. Persistent iron loading transforms lysossomes into siderosomes, after which haemosiderin may be formed by grandual transformation of ferritin. The bone marrow reticulum cell shows evidence suggestive of autophagy, a process which may allow for the transfer of cell sap ferritin into lysosomes, as documented for other types of iron storing cells.
骨髓网状细胞中铁的细胞内运输和储存可通过识别铁大分子在电子显微镜下进行研究。在人为增加骨髓红细胞吞噬作用后，铁蛋白分子在红细胞破碎网状细胞的细胞液和溶酶体中均有积累。持续的铁负荷将溶酶体转化为含铁小体，之后铁蛋白可通过逐渐转化形成含铁血黄素。骨髓网状细胞显示出自噬迹象，这一过程可能使细胞液中的铁蛋白转移至溶酶体，其他类型的储铁细胞也有相关记录。
