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肾移植受者发生热带肌炎和新月体性肾小球肾炎的首例报告。

First report of tropical myositis and crescentic glomerulonephritis in a renal transplant recipient.

作者信息

Jha V, Swaminathan S, Joshi K, Kohli H S, Sud K, Gupta K L, Sakhuja V

机构信息

Departments of Nephrology and Histopathology, Postgraduate Institute of Medical Education and Research, Chandigarh, India.

出版信息

Am J Kidney Dis. 1999 Dec;34(6):E25. doi: 10.1016/S0272-6386(99)70030-2.

Abstract

We describe a renal transplant recipient who presented with tropical myositis and acute allograft dysfunction 2(1/2) years after transplantation. Graft biopsy showed immune-complex crescentic glomerulonephritis. He was receiving only 7.5 mg/d of prednisolone for more than 2 months before presentation. Renal function did not improve despite treatment with antibiotics, methylprednisolone pulse therapy, and cyclophosphamide. He died of septicemia.

摘要

我们描述了一名肾移植受者,其在移植后2年半出现热带肌炎和急性移植肾功能障碍。移植肾活检显示为免疫复合物新月体性肾小球肾炎。在出现症状前两个多月,他仅接受每日7.5毫克的泼尼松龙治疗。尽管使用了抗生素、甲泼尼龙冲击疗法和环磷酰胺进行治疗,但其肾功能并未改善。他死于败血症。

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