Wiklund L
Acta Anaesthesiol Scand Suppl. 1975;58:29-40. doi: 10.1111/j.1399-6576.1975.tb05420.x.
In 34 patients with gallbladder disease, but otherwise healthy, the systemic and splanchnic oxygen uptake were studied in connection with cholecystectomy. Postoperatively, 22 patients were given a posterior splanchnic blockade with 0.5% plain lidocaine, and 12 were given fentanyl intramuscularly in a dose of 3.5 mug/kg b.w. Postoperatively, before the analgesic agent was administered, both the systemic and splanchnic oxygen uptake were increased by 40--50%, the splanchnic fraction of the systemic oxygen uptake being the same as preoperatively. Following administration of fentanyl, as well as after splanchnic blockade, the systemic oxygen uptake decreased almost to the preoperative level. The splanchnic oxygen uptake, however, did not change after fentanyl administration but increased further significantly following splanchnic blockade. The splanchnic fraction of the systemic oxygen uptake increased rapidly after the blockade, while it increased slowly after fentanyl administration.
对34例患有胆囊疾病但其他方面健康的患者，在胆囊切除术过程中研究了全身和内脏氧摄取情况。术后，22例患者接受了0.5%普通利多卡因的内脏后阻滞，12例患者肌肉注射剂量为3.5μg/kg体重的芬太尼。术后，在给予镇痛剂之前，全身和内脏氧摄取均增加了40% - 50%，全身氧摄取的内脏部分与术前相同。给予芬太尼后以及内脏阻滞后，全身氧摄取几乎降至术前水平。然而，芬太尼给药后内脏氧摄取没有变化，但内脏阻滞后进一步显著增加。内脏阻滞后全身氧摄取的内脏部分迅速增加，而芬太尼给药后则缓慢增加。
