孕期急性白血病的治疗。

Treatment of acute leukemia during pregnancy.

作者信息

Raich P C, Curet L B

出版信息

Cancer. 1975 Sep;36(3):861-2. doi: 10.1002/1097-0142(197509)36:3<861::aid-cncr2820360305>3.0.co;2-p.

DOI:10.1002/1097-0142(197509)36:3<861::aid-cncr2820360305>3.0.co;2-p

Abstract

Cytarabine and thioguanine therapy for acute myelocytic leukemia, initiated during the 26th week of pregnancy, led to complete remission of the leukemia in a 22-year-old woman, and allowed for delivery of a normal infant at term. No chromosomal abnormalities were detected in the infant. Cytarabine and thioguanine in combination are effective agents in the treatment of acute leukemia in adults. Their use appears warranted in pregnant patients after the first trimester.

摘要

在妊娠第26周开始使用阿糖胞苷和硫鸟嘌呤治疗一名22岁女性的急性髓细胞白血病，白血病完全缓解，并足月分娩一名正常婴儿。婴儿未检测到染色体异常。阿糖胞苷和硫鸟嘌呤联合使用是治疗成人急性白血病的有效药物。在孕早期过后的孕妇中使用似乎是合理的。