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癌症部位之间的家族关联。

Familial associations between cancer sites.

作者信息

Thomas A, Cannon-Albright L, Bansal A, Skolnick M H

机构信息

Myriad Genetics Inc., 390 Wakara Way, Salt Lake City, Utah 84108, USA.

出版信息

Comput Biomed Res. 1999 Dec;32(6):517-29. doi: 10.1006/cbmr.1999.1525.

Abstract

The Utah Population Database links together genealogical records, the Utah Cancer Registry, and Utah death certificates and allows identification of cancer clusters. Groups of individuals with cancers of some types tend to fall into related clusters within the genealogy. We examine the apparent tendency of cases of two types of cancer to cluster together and distinguish real clusters from chance occurrences. Some established associations are found, whereas some are surprisingly absent. Some new associations are also suggested.

摘要

犹他州人口数据库将家谱记录、犹他州癌症登记处和犹他州死亡证明联系在一起,能够识别癌症聚集情况。某些类型癌症患者群体往往在家谱中形成相关的聚集群组。我们研究了两种癌症病例明显的聚集倾向,并区分真实的聚集群组和偶然发生的情况。我们发现了一些已确定的关联,而有些关联却出人意料地不存在。还提出了一些新的关联。

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