Rivera R, Cangir A, Strong L
South Med J. 1975 Nov;68(11):1391-4. doi: 10.1097/00007611-197511000-00017.
Incontinentia pigmenti, a syndrome of developmental defects, was found to be associated with acute granulocytic leukemia in a 4-month-old black girl. She has been responsive to antileukemic drugs, and remission has been induced without difficulty after each relapse. Although survival time was expected to be very short because of her age, race, type of leukemia, and initial peripheral leukocyte count at time of diagnosis, she is still alive 35 months after diagnosis of leukemia. One may speculate that the prolonged survival time might be related to the unknown genetic defect.
色素失禁症是一种发育缺陷综合征，在一名4个月大的黑人女孩中发现与急性粒细胞白血病相关。她对抗白血病药物有反应，每次复发后都能顺利诱导缓解。尽管由于她的年龄、种族、白血病类型以及诊断时的初始外周白细胞计数，预计生存时间会非常短，但她在白血病诊断后35个月仍然存活。人们可能推测，延长的生存时间可能与未知的基因缺陷有关。
