对聚乙二醇和呋喃西林的过敏性接触性皮炎

Allergic contact dermatitis to polyethylene glycol and nitrofurazone.

作者信息

Guijarro S C, Sánchez-Pérez J, García-Díez A

机构信息

Department of Dermatology, Hospital Universitario de la Princesa, Madrid, Spain.

出版信息

Am J Contact Dermat. 1999 Dec;10(4):226-7. doi: 10.1053/AJCD01000226.

DOI:10.1053/AJCD01000226

PMID:10594300

Abstract

We report a case of worsening dermatitis after the application of an antibiotic ointment (Furacin) containing furazone and polyethylene glycol. Patch tests to nickel sulfate, potassium dischromate, chloride cobalt, Furacin, nitrofurazone 1% petrolatum, polyethylene glycol mix 4% petrolatum, polyethylene glycol (PEG) 300 4% petrolatum, and PEG 400 as is (ai) were positive. The use of topical agents containing nitrofurazone or polyethylene glycol on damaged skin may predispose to contact allergy. We discuss the sensitizing properties of nitrofurazone and polyethylene glycol.

摘要

我们报告了一例在应用含有呋喃西林和聚乙二醇的抗生素软膏（呋锌膏）后皮炎加重的病例。对硫酸镍、重铬酸钾、氯化钴、呋锌膏、1%凡士林的呋喃西林、4%凡士林的聚乙二醇混合物、4%凡士林的聚乙二醇（PEG）300以及原样的PEG 400进行的斑贴试验呈阳性。在受损皮肤上使用含有呋喃西林或聚乙二醇的局部用药可能易引发接触性过敏。我们讨论了呋喃西林和聚乙二醇的致敏特性。