Moreno-Lozano Lucía, de Aramburu-Mera Teresa, Bermúdez-Hormigo Carmen
Servicio de Alergología, Hospital Punta Europa, Algeciras (Cádiz), España.
Rev Alerg Mex. 2024 Jun 30;71(2):128-130. doi: 10.29262/ram.v71i2.1246.
Allergic sensitization to topical antimicrobial treatments is a well-known problem. Furacin® is one of the most widely used in our environment. It contains 0.2% nitrofurazone and polyethylene glycol (PEG) as a vehicle.
57-year-old male with no history of interest. He presented skin rash, blisters, and serous exudate 2-3 days after starting treatment with Furacin® (applied to an infected skin wound). Epicutaneous tests were performed with a true test battery, nitrofurantoin 1% in petrolatum, PEG15000 and 4000 1% in petrolatum, pure PEG 400, PEG monomethyl ether 350 1% in water. Positive result at 96 hours for nitrofurantoin.
Nitrofurazone is widely used as a topical antibiotic because of its bactericidal spectrum. It (including its excipients) should be considered in case of adverse reactions after application.
对抗菌外用治疗产生过敏致敏是一个众所周知的问题。呋西林是我们环境中使用最广泛的药物之一。它含有0.2%的呋喃西林和作为载体的聚乙二醇（PEG）。
一名57岁男性，无相关病史。在开始使用呋西林（用于感染的皮肤伤口）治疗2 - 3天后，他出现了皮疹、水疱和浆液性渗出物。使用真正的测试组进行了皮肤试验，包括凡士林基质中1%的呋喃妥因、凡士林基质中1%的PEG15000和4000、纯PEG 400、水中1%的聚乙二醇单甲醚350。呋喃妥因在96小时时呈阳性结果。
呋喃西林因其杀菌谱而被广泛用作外用抗生素。在应用后出现不良反应的情况下，应考虑它（包括其辅料）。
