镓-67单光子发射计算机断层扫描在监测蝶窦侵袭性曲霉病治疗效果中的价值
Value of Ga-67 SPECT in monitoring the effects of therapy in invasive aspergillosis of the sphenoid sinus.
作者信息
Tzen K Y, Yen T C, Lin K J
机构信息
Department of Nuclear Medicine, Chang Gung Memorial Hospital, Taipei Medical Center and School of Medicine, Chang Gung University, Taiwan.
出版信息
Clin Nucl Med. 1999 Dec;24(12):938-41. doi: 10.1097/00003072-199912000-00006.
PURPOSE
We report a case of invasive sphenoid sinus aspergillosis clinically presenting as a pituitary mass.
METHODS
After exploration via the trans-sphenoidal approach and subsequent treatment with amphotericin-B, Ga-67 brain SPECT was performed twice to monitor the therapeutic effect.
RESULTS
Three months after antifungal treatment, Ga-67 brain SPECT showed partial resolution of the lesion in the sella turcica region. The patient continued with fluconazole treatment for another 2 months and received another Ga-67 brain SPECT, which showed complete clearing of the previous lesion.
CONCLUSION
Ga-67 brain SPECT may play a potentially useful role in monitoring the therapeutic effect of treatment of invasive sphenoid sinus aspergillosis.
目的
我们报告一例侵袭性蝶窦曲霉菌病，临床上表现为垂体肿块。
方法
经蝶窦入路探查并随后用两性霉素B治疗后，进行了两次Ga-67脑单光子发射计算机断层扫描（SPECT）以监测治疗效果。
结果
抗真菌治疗三个月后，Ga-67脑SPECT显示蝶鞍区病变部分消退。患者继续用氟康唑治疗另外2个月，并接受了另一次Ga-67脑SPECT检查，结果显示先前病变完全清除。
结论
Ga-67脑SPECT在监测侵袭性蝶窦曲霉菌病治疗效果方面可能发挥潜在的有用作用。
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