Tzen K Y, Yen T C, Lin K J
Department of Nuclear Medicine, Chang Gung Memorial Hospital, Taipei Medical Center and School of Medicine, Chang Gung University, Taiwan.
Clin Nucl Med. 1999 Dec;24(12):938-41. doi: 10.1097/00003072-199912000-00006.
We report a case of invasive sphenoid sinus aspergillosis clinically presenting as a pituitary mass.
After exploration via the trans-sphenoidal approach and subsequent treatment with amphotericin-B, Ga-67 brain SPECT was performed twice to monitor the therapeutic effect.
Three months after antifungal treatment, Ga-67 brain SPECT showed partial resolution of the lesion in the sella turcica region. The patient continued with fluconazole treatment for another 2 months and received another Ga-67 brain SPECT, which showed complete clearing of the previous lesion.
Ga-67 brain SPECT may play a potentially useful role in monitoring the therapeutic effect of treatment of invasive sphenoid sinus aspergillosis.
我们报告一例侵袭性蝶窦曲霉菌病，临床上表现为垂体肿块。
经蝶窦入路探查并随后用两性霉素B治疗后，进行了两次Ga-67脑单光子发射计算机断层扫描（SPECT）以监测治疗效果。
抗真菌治疗三个月后，Ga-67脑SPECT显示蝶鞍区病变部分消退。患者继续用氟康唑治疗另外2个月，并接受了另一次Ga-67脑SPECT检查，结果显示先前病变完全清除。
Ga-67脑SPECT在监测侵袭性蝶窦曲霉菌病治疗效果方面可能发挥潜在的有用作用。
