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[33年随访研究中视网膜海绵状血管瘤合并脑内海绵状血管瘤]

[Retinal cavernous hemangioma associated with intracerebral cavernous hemangioma in a 33-year follow-up study].

作者信息

Skoumalová S, Boguszaková J

机构信息

Ocní klinika VFN a 1. LF UK, Praha.

出版信息

Cesk Slov Oftalmol. 1999 Sep;55(5):316-22.

Abstract

Cavernous hemangioma of the retina is congenital, mostly unilateral lesion, with autosomal dominant transmission. Usually can be easily recognized by its characteristic appearance of cluster of dark-red saccular aneurysms, partly covered by a fine glial membrane. It may be associated with similar lesions of the skin, brain and other organs. A 23-year-old patient with cavernous hemangioma of the retina, who preventively underwent argon laser therapy has been followed up in our department. During the observation no symptomatic ocular hemorrhage occurred. We presuppose that a preventive laser treatment forestalled a possible retinal and vitreous bleeding. However, in a long-term follow up we have detected slowly growing number of retinal hemangiomas. Patient's life is hardly damaged by complications of cavernous hemangioma of the brain. Because of autosomal dominant transmission all family members, with and without fundus findings, should undergo computed tomography or magnetic resonance imagining of the brain to preclude intracranial vascular anomaly.

摘要

视网膜海绵状血管瘤是先天性的,大多为单侧病变,呈常染色体显性遗传。通常可因其特征性的暗红色囊状动脉瘤簇外观而容易识别,部分被一层薄的神经胶质膜覆盖。它可能与皮肤、脑和其他器官的类似病变相关。一名患有视网膜海绵状血管瘤的23岁患者在我院接受了预防性氩激光治疗并进行了随访。在观察期间未发生有症状的眼部出血。我们推测预防性激光治疗预防了可能的视网膜和玻璃体出血。然而,在长期随访中我们发现视网膜血管瘤数量在缓慢增加。脑部海绵状血管瘤的并发症对患者生活几乎没有损害。由于常染色体显性遗传,所有家庭成员,无论有无眼底表现,均应接受脑部计算机断层扫描或磁共振成像,以排除颅内血管异常。

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