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一个患有遗传性脑内海绵状血管瘤的家族。

A family with hereditary intracerebral cavernous angiomas.

作者信息

Traverso F, Passeri F, Pedrinazzi E, Reduzzi L

机构信息

Divisione di Neurologia, Ospedale Maggiore di Crema, USL 53.

出版信息

Riv Neurol. 1991 Mar-Apr;61(2):71-3.

PMID:1887200
Abstract

There are a very few reports in literature of inherited intracerebral cavernous angiomas. The majority of them are Mexican-American families. In some of the reported families autosomal dominant transmission is suggested. We report a family in which three members of three consecutive generations were proven to have multiple intracerebral cavernous malformations, without involvement of skin, eyes, or other viscera. An autosomal dominant mode of inheritance is clearly suggested.

摘要

文献中关于遗传性脑内海绵状血管瘤的报道极少。其中大多数是墨西哥裔美国家庭。在一些已报道的家族中提示为常染色体显性遗传。我们报告了一个家族,连续三代中的三名成员被证实患有多发性脑内海绵状畸形,皮肤、眼睛或其他内脏未受累。明显提示为常染色体显性遗传模式。

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