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[抗生素时代耳源性脓毒症的临床与治疗方面]

[Clinical and therapeutic aspects of otogenic sepsis in the antibiotic era].

作者信息

Gadzhimirzaev G A

出版信息

Vestn Otorinolaringol. 1999(6):24-7.

PMID:10596597
Abstract

152 cases of otogenic thrombophlebitis of the sigmoid sinus (TSS) are analysed. 128 (84.2%) patients had thrombophlebitis and sepsis, 24 (15.8%) had thrombophlebitis without sepsis. TSS occurred more frequently in combination with other intracranial complications. In conditions of wide use of antibiotics and other drugs thromboembolic and toxicoinfectious otogenic complications may run with an atypical clinical picture: with reduced symptoms, without classic manifestations of sepsis. In diagnosis such investigations as computed tomography, MR-tomography, ultrasonography may be decisive. Major diagnostic criterium in diagnosis of otogenic sepsis is polyorganic insufficiency. Otogenic thrombophlebitis and sepsis is treated first of all surgically--the purulent focus in the ear should be cleansed. Postoperative treatment includes antimicrobial drugs, immunomodulators, anticoagulants, antihistaminic, detoxicating and antiedematic medicines, UV irradiation of autoblood and hyperbaric oxygenation.

摘要

对152例乙状窦血栓性静脉炎(TSS)进行了分析。128例(84.2%)患者患有血栓性静脉炎和败血症,24例(15.8%)患有无败血症的血栓性静脉炎。TSS更常与其他颅内并发症同时发生。在广泛使用抗生素和其他药物的情况下,血栓栓塞性和中毒感染性耳源性并发症可能呈现非典型临床表现:症状减轻,无败血症的典型表现。在诊断中,计算机断层扫描、磁共振断层扫描、超声检查等检查可能起决定性作用。耳源性败血症诊断的主要标准是多器官功能不全。耳源性血栓性静脉炎和败血症首先应进行手术治疗——应清除耳部的脓性病灶。术后治疗包括抗菌药物、免疫调节剂、抗凝剂、抗组胺药、解毒和消肿药物、自体血紫外线照射和高压氧治疗。

相似文献

1
[Clinical and therapeutic aspects of otogenic sepsis in the antibiotic era].[抗生素时代耳源性脓毒症的临床与治疗方面]
Vestn Otorinolaringol. 1999(6):24-7.
2
[Treatment policy in thrombophlebitis lesions of the sigmoid sinus and internal jugular vein during intensive use of antibiotics].[在大量使用抗生素期间乙状窦和颈内静脉血栓性静脉炎病变的治疗策略]
Vestn Otorinolaringol. 2001(3):55-7.
3
[Differential diagnosis of otogenic thrombophlebitis of the venous sinuses of the dura mater and sepsis].[硬脑膜静脉窦耳源性血栓性静脉炎与败血症的鉴别诊断]
Vestn Otorinolaringol. 1983 Jul-Aug(4):21-5.
4
[Clinical and therapeutic aspects of otogenic thrombophlebitis].
Rev Chir Oncol Radiol O R L Oftalmol Stomatol Otorinolaringol. 1983 Oct-Dec;28(4):271-5.
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[Clinical aspects and treatment of otogenic sepsis].[耳源性脓毒症的临床症状与治疗]
Vestn Otorinolaringol. 1983 Jul-Aug(4):16-20.
6
[Characteristics of the pathogenesis and clinical picture of otogenic sepsis].[耳源性败血症的发病机制及临床表现特征]
Sov Med. 1985(10):108-10.
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[Thrombophlebitis of the sigmoid sinus and otogenic sepsis].[乙状窦血栓性静脉炎与耳源性败血症]
Srp Arh Celok Lek. 1991 May-Jun;119(5-6):143-4.
8
Otogenic thrombosis of the lateral sinus: report of a case in a child.
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[Facial nerve paralysis as a sequelae of chronic suppurative otitis].[面神经麻痹作为慢性化脓性中耳炎的后遗症]
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[Modern characteristics of clinical course and treatment of otogenic purulent meningitis].[耳源性化脓性脑膜炎的临床病程及治疗的现代特征]
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引用本文的文献

1
[Diagnosis and treatment of otogenic sigmoid sinus thrombophlebitis].耳源性乙状窦血栓性静脉炎的诊断与治疗
Lin Chuang Er Bi Yan Hou Tou Jing Wai Ke Za Zhi. 2023 Feb;37(2):116-121. doi: 10.13201/j.issn.2096-7993.2023.02.008.