两性霉素B治疗的念珠菌性关节炎。
Candida arthritis treated with amphotericin B.
作者信息
Poplack D G, Jacobs S A
出版信息
J Pediatr. 1975 Dec;87(6 Pt 1):989-90. doi: 10.1016/s0022-3476(75)80926-7.
PMID:1059760
Abstract
This report describes a patient with acute lymphoblastic leukemia who developed arthritis of the knee caused by Candida tropicalis. Systemic therapy with amphotericin B apparently suppressed but did not eliminate the infection. Resolution of the arthritis occurred only after three intra-articular injections of amphotericin B. Intra-articular administration of amphotericin B may be a useful adjunct to systemic antifungal therapy in the treatment of these infections.
摘要
本报告描述了一名急性淋巴细胞白血病患者，该患者发生了由热带念珠菌引起的膝关节炎。两性霉素B全身治疗似乎抑制了感染，但并未消除感染。仅在关节腔内注射三次两性霉素B后，关节炎才得以缓解。关节腔内注射两性霉素B可能是全身抗真菌治疗这些感染的有用辅助手段。
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