Junewick J J, Fitzgerald N E
DeVos Children's Hospital, Grand Rapids, MI 49503, USA.
Pediatr Radiol. 1999 Dec;29(12):904-7. doi: 10.1007/s002470050722.
To determine the frequency of thymic involvement in Langerhans' cell histiocytosis and describe its imaging appearance before and after treatment.
A retrospective review of the radiology and clinical records of all patients diagnosed with Langerhans' cell histiocytosis at DeVos Children's Hospital between 1992 and 1998.
Of the 14 patients diagnosed with Langerhans' cell histiocytosis, 7 demonstrated multisystem involvement. The thymus was involved in 5 of 7 patients. The thymus was enlarged in 5; thymic contours were nodular/lobulated in 2; cystic changes were noted in 4; and dystrophic vascular-appearing calcifications were seen in 1. In all cases, findings regressed or resolved following chemotherapy.
The thymus is commonly involved in Langerhans' cell histiocytosis, especially in multisystem disease. Radiologically, the thymus is enlarged and may be smooth or lobulated/nodular in contour, possibly containing cysts and calcifications.
确定朗格汉斯细胞组织细胞增多症中胸腺受累的频率，并描述其治疗前后的影像学表现。
回顾性分析1992年至1998年间在德沃斯儿童医院诊断为朗格汉斯细胞组织细胞增多症的所有患者的放射学和临床记录。
在14例诊断为朗格汉斯细胞组织细胞增多症的患者中，7例表现为多系统受累。7例患者中有5例胸腺受累。5例胸腺增大；2例胸腺轮廓呈结节状/分叶状；4例有囊性改变；1例可见营养不良性血管样钙化。在所有病例中，化疗后病变均消退或缓解。
胸腺在朗格汉斯细胞组织细胞增多症中常见受累，尤其是在多系统疾病中。在放射学上，胸腺增大，轮廓可能光滑或呈分叶状/结节状，可能含有囊肿和钙化。
Zotero 插件