支原体脂蛋白与宿主免疫系统之间的相互作用。

Interactions between mycoplasma lipoproteins and the host immune system.

作者信息

Chambaud I, Wróblewski H, Blanchard A

机构信息

Institut Pasteur, Unité d'Oncologie Virale, 28 rue du Dr Roux, 75724 Paris Cedex 15, France.

出版信息

Trends Microbiol. 1999 Dec;7(12):493-9. doi: 10.1016/s0966-842x(99)01641-8.

DOI:10.1016/s0966-842x(99)01641-8

PMID:10603485

Abstract

Mycoplasmas typically have a number of distinct lipoproteins anchored on the outer face of the plasma membrane. These surface antigens have a potent modulin activity and are preferential targets of the host immune response. However, the variation of some of these lipoproteins provides mycoplasmas with an effective means of evading the host immune defence system.

摘要

支原体通常有许多不同的脂蛋白锚定在质膜的外表面。这些表面抗原具有强大的调节蛋白活性，是宿主免疫反应的优先靶点。然而，其中一些脂蛋白的变异为支原体提供了一种有效逃避宿主免疫防御系统的手段。