Sillén U, Sölsnes E, Hellström A L, Sandberg K
Department of Pediatric Surgery, University Hospital, Ostra, Göteborg, Sweden.
J Urol. 2000 Jan;163(1):278-81. doi: 10.1016/s0022-5347(05)68036-6.
To elucidate further the maturation of voiding habits from gestation to infancy we investigated the free voiding pattern of healthy preterm neonates.
We evaluated 11 male and 8 female healthy preterm newborns at a mean of 32 weeks after cessation of menstrual flow (postmenstrual age). Assessment was done in the neonatal ward using 4-hour voiding observation, a method described previously in studies of free voiding pattern of full-term newborns.
The voiding pattern of male and female preterm neonates was characterized by 1 void per hour and a mean voided volume of 53% of bladder capacity with 58% frequency of interrupted voiding. Residual urine was increased but varied during observation (mean 11% bladder capacity) and was 0 after at least 1 void during 4 hours in 14 of the 19 subjects. Two-thirds of all voiding occurred during sleep, whereas a third of the newborns showed signs of arousal with a mean awake time of only 17 minutes.
The voiding pattern of preterm versus full-term subjects is characterized by an increased number of interrupted voidings, further indicating that these voidings represent immature behavior of detrusor-sphincter coordination. Also, the high number of voidings during sleep suggest a more immature pattern for preterm newborns.
为了进一步阐明从妊娠期到婴儿期排尿习惯的成熟过程，我们对健康的早产新生儿的自由排尿模式进行了研究。
我们评估了11名男性和8名女性健康早产新生儿，平均月经停止后32周（孕龄）。在新生儿病房采用4小时排尿观察法进行评估，该方法先前已在足月新生儿自由排尿模式的研究中有所描述。
早产男、女新生儿的排尿模式特点为每小时排尿1次，平均排尿量为膀胱容量的53%，排尿中断频率为58%。残余尿量增加，但在观察期间有所变化（平均为膀胱容量的11%），19名受试者中有14名在4小时内至少排尿1次后残余尿量为0。三分之二的排尿发生在睡眠期间，而三分之一的新生儿表现出觉醒迹象，平均清醒时间仅为17分钟。
与足月儿相比，早产儿的排尿模式特点是排尿中断次数增加，这进一步表明这些排尿代表了逼尿肌-括约肌协调的不成熟行为。此外，睡眠期间排尿次数多表明早产儿的排尿模式更不成熟。
