High coumarin 7-hydroxylase activity does not protect mice against Warfarin.
作者信息
Lush I E, Arnold C J
出版信息
Heredity (Edinb). 1975 Oct;35(2):279-81. doi: 10.1038/hdy.1975.92.
PMID:1060612
Abstract
Sixteen strains of mice varied widely in their ability to 7-hydroxylate injected coumarin to form umbelliferone, which is excreted in the urine. The same strains also varied in their resistance to the lethal effects of dietary Warfarin. There was no correlation between hydroxylating ability and Warfarin resistance.
摘要
Zotero 插件