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复发性腹痛的一个不寻常原因。

An unusual cause of recurrent abdominal pain.

作者信息

Jongnarangsin K, Mukherjee S, Bauer M A

机构信息

Department of Medicine, Bassett Hospital, Cooperstown, New York 13326, USA.

出版信息

Am J Gastroenterol. 1999 Dec;94(12):3620-2. doi: 10.1111/j.1572-0241.1999.01619.x.

Abstract

Abdominal pain is a common complaint with diverse etiologies. We describe an unusual case of recurrent abdominal pain in an adult due to lead poisoning, a condition usually associated with childhood. A previously healthy 42-yr-old man presented with 2 days of severe crampy abdominal pain and a 1-month history of constipation. Physical examination was remarkable for diffuse abdominal pain but peritoneal signs were not present. Blood tests were remarkable for hematocrit of 33 and mean cell volume of 78, with ovalocytes and basophilic stippling on blood smear. Abdominal x-ray showed stool throughout the colon and a nonspecific bowel gas pattern. The patient was treated with intravenous fluids and enemas, and his symptoms resolved within 2 days. Repeat history taking revealed he had been stripping paint from an old Victorian house in the preceding few months. He was discharged after a blood lead level was obtained. Before his clinic appointment he was readmitted 2 days later with recurrent abdominal pain. His blood lead level was elevated at 110 microg/dl (toxic range). After consultation with the Occupational Health and Safety Administration and local poison control service, he was treated with intravenous calcium edetate disodium and intramuscular dimercaprol. He was asymptomatic at discharge, with a level of 56 microg/dl. Two weeks later, a repeat level was elevated at 72 microg/dl, for which he received a 3-wk course of oral dimercaptosuccimer. Subsequent levels were unremarkable, and the patient remains asymptomatic. Abdominal pain secondary to lead poisoning in adults is uncommon. This case highlights the importance of taking a detailed occupational history and appropriately using "routine" blood tests to diagnose a rare condition that presented with a common complaint.

摘要

腹痛是一种病因多样的常见病症。我们描述了一例成人因铅中毒反复腹痛的罕见病例,铅中毒通常与儿童期相关。一名既往健康的42岁男性,出现了两天严重的痉挛性腹痛,并有1个月的便秘史。体格检查显示全腹压痛明显,但无腹膜刺激征。血液检查显示血细胞比容为33,平均红细胞体积为78,血涂片可见椭圆形红细胞和嗜碱性点彩。腹部X线显示结肠内充满粪便,肠气分布无特异性。患者接受了静脉补液和灌肠治疗,症状在2天内缓解。再次询问病史发现,他在前几个月一直在刮除一座古老维多利亚式房屋的油漆。在获得血铅水平后他出院了。在门诊预约前,他于两天后因反复腹痛再次入院。他的血铅水平升高至110微克/分升(中毒范围)。在咨询职业健康与安全管理局和当地毒物控制中心后,他接受了静脉注射依地酸钙钠和肌肉注射二巯丙醇治疗。出院时他无症状,血铅水平为56微克/分升。两周后,复查血铅水平升高至72微克/分升,为此他接受了为期3周的口服二巯基丁二酸治疗。随后的血铅水平正常,患者仍无症状。成人铅中毒继发腹痛并不常见。该病例强调了详细询问职业病史以及合理运用“常规”血液检查来诊断以常见症状表现的罕见病症的重要性。

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