脂蛋白对宿主造成损害。

Lipoproteins take their toll on the host.

作者信息

Janeway C A, Medzhitov R

机构信息

Section of Immunobiology, Yale University School of Medicine, P.O. Box 208011, New Haven, 06520-8011, USA.

出版信息

Curr Biol. 1999 Dec 2;9(23):R879-82. doi: 10.1016/s0960-9822(00)80073-1.

DOI:10.1016/s0960-9822(00)80073-1

PMID:10607553

Abstract

A family of mammalian Toll-like receptors (TLRs) has a critical role in the recognition of microbial infection. Recent evidence suggests that bacterial lipoproteins - major components of bacterial cell walls - are recognized by a member of the human TLR family.

摘要

哺乳动物Toll样受体（TLR）家族在识别微生物感染中起关键作用。最近的证据表明，细菌脂蛋白（细菌细胞壁的主要成分）可被人类TLR家族的一个成员识别。