Kaddu S, Schäppi H, Kerl H, Soyer H P
Department of Dermatology, University of Graz, Austria.
Am J Dermatopathol. 1999 Dec;21(6):552-6. doi: 10.1097/00000372-199912000-00009.
We report two cases of an unusual combined adnexal neoplasm arising in a nevus sebaceus (NS). Clinically, both neoplasms presented in two women (46 and 78 years) as single, partially ulcerated nodules within NS situated on the scalp. Histopathologically, each neoplasm showed distinctive aggregations of basaloid cells with features of trichoblastoma adjacent to aggregations of neoplastic cells exhibiting features of sebaceoma. In both cases, typical features of NS were present. To the best of our knowledge, this unusual combined adnexal neoplasm comprised of trichoblastoma and sebaceoma could not be assigned to any previously described histopathologic entity. This "complex" adnexal neoplasm should be distinguished histopathologically from basal cell carcinoma with sebaceous differentiation and trichoblastoma with sebaceous differentiation.
我们报告了两例发生于皮脂腺痣（NS）的罕见的联合附件肿瘤病例。临床上，这两种肿瘤均表现为两名女性（分别为46岁和78岁）头皮上皮脂腺痣内单个的、部分溃疡的结节。组织病理学上，每种肿瘤均显示基底样细胞的独特聚集，具有毛母细胞瘤的特征，毗邻表现为皮脂腺瘤特征的肿瘤细胞聚集。两例均存在皮脂腺痣的典型特征。据我们所知，这种由毛母细胞瘤和皮脂腺瘤组成的罕见联合附件肿瘤无法归入任何先前描述的组织病理学实体。这种“复杂”的附件肿瘤在组织病理学上应与具有皮脂腺分化的基底细胞癌和具有皮脂腺分化的毛母细胞瘤相鉴别。
