乳腺癌预防试验：有风险的女性应该服用他莫昔芬吗？

The breast cancer prevention trial: should women at risk take tamoxifen?

作者信息

McKeon V A

机构信息

Saint Anselm College in Manchester, NH, USA.

出版信息

J Obstet Gynecol Neonatal Nurs. 1999;28(6 Suppl 1):34-8.

PMID:10608495

Abstract

Tamoxifen is nonsteroidal antiestrogen originally developed in 1996 as a contraceptive. Recently, tamoxifen has been under study within the massive Breast Cancer Prevention Trial-but have we learned enough to recommend tamoxifen for breast cancer prevention? This article looks at the drug therapies, including tamoxifen, currently under development for fighting and preventing breast cancer.

摘要

他莫昔芬是一种非甾体类抗雌激素药物，最初于1966年作为避孕药研发。最近，他莫昔芬一直在大规模乳腺癌预防试验中接受研究——但我们是否已经了解得足够多，可以推荐使用他莫昔芬来预防乳腺癌呢？本文探讨了目前正在研发的用于抗击和预防乳腺癌的药物疗法，包括他莫昔芬。