Daum R
Langenbecks Arch Chir. 1975 Nov;339:347-50. doi: 10.1007/BF01257528.
Of the malignant bone tumors that occur in childhood, chondrosarcoma, osteosarcoma, and Ewing's sarcoma are of special interest with regard to therapeutic approach. Whereas in chondrosarcoma radical surgery is the treatment of choice, due to its resistance to radiation, the most efficient treatment for osteosarcoma and Ewing's sarcoma has not yet been clearly defined. In the light of recepnt developments, delayed surgery following initial radiation in osteosarcoma, as advocated by Cade in 1947, has now been superseded by immediate amputation. In Ewing's sarcoma, radiation appears to be superior to surgical intervention, according to recent publications.
在儿童期发生的恶性骨肿瘤中,软骨肉瘤、骨肉瘤和尤因肉瘤在治疗方法方面具有特殊意义。软骨肉瘤由于对放疗有抗性,根治性手术是首选治疗方法,而骨肉瘤和尤因肉瘤最有效的治疗方法尚未明确界定。根据最近的进展,1947年凯德所倡导的骨肉瘤初始放疗后延迟手术,现已被立即截肢所取代。根据最近的出版物,在尤因肉瘤中,放疗似乎优于手术干预。