Ahlberg M, Bawden J W, Hammarström L E, Hellborg R
Odontol Revy. 1975;26(4):267-79.
Proton activation analysis, using the reactions 19F(p, alpha gamma)16O and 15N(p, alpha gamma)12C, was employed to study the fluorine and nitrogen content of developing rat molar enamel at various stages of maturation. Four groups of rats were utilized: Group I -- injected intraperitoneally at 6 days of age with 20 mg F/kg b.w. as sodium fluoride solution and terminated at 30 minutes and 1, 5 and 9 days postinjection; Group II -- injected in a similar way at 7 days of age and terminated 30 minutes and 1, 4 and 8 days postinjection; Group III -- injected with 10 mg F/kg, at 6, 15 and 19 days of age and terminated 30 minutes later; Group IV -- control animals injected with distilled water at 6 and 15 days of age respectively and terminated 30 minutes later. Analysis reflected decreasing nitrogen content in the enamel as maturation proceeded. However, fluorine concentrations were highest in all groups at the earlier stages of enamel development.
利用反应19F(p, αγ)16O和15N(p, αγ)12C的质子活化分析，研究了发育中大鼠磨牙釉质在不同成熟阶段的氟和氮含量。使用了四组大鼠：第一组——在6日龄时腹腔注射20毫克氟/千克体重的氟化钠溶液，并在注射后30分钟、1、5和9天处死；第二组——在7日龄时以类似方式注射，并在注射后30分钟、1、4和8天处死；第三组——在6、15和19日龄时注射10毫克氟/千克体重，并在30分钟后处死；第四组——对照动物分别在6和15日龄时注射蒸馏水，并在30分钟后处死。分析表明，随着成熟过程的进行，釉质中的氮含量降低。然而，在釉质发育的早期阶段，所有组中的氟浓度最高。
