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[与妊娠结局相关的无症状羊膜腔感染]

[Symptomless amniotic infection related to pregnancy outcome].

作者信息

Horváth B, Kneffel P, Grasselly M, Csanaky G, Lakatos F

机构信息

Vas megyei Markusovszky Kórház, Szombathely, Szülészet-Nögyógyászati Osztály.

出版信息

Orv Hetil. 1999 Nov 21;140(47):2627-31.

Abstract

Placental histology in 984 pregnancies (758 term and 226 preterm) occurring during the years 1995 to 1998 was investigated and amniotic cavity cultures were taken during 918 cesarean sections. Histology revealed placental infection in 20.3% of placentas. Chorioamnionitis was confirmed in 119 out of 758 term pregnancies (15.7%) while in 81 out of 226 preterm pregnancies (35.8%); the difference is highly significant (chi 2 = 26.6, p < 0.01). Bacteriological culture resulted in bacterial growth in 19.7% of all cases (181/918), its frequency was significant higher in premature births (54/133, 40.3% chi 2 = 25.2, p < 0.01) as compared with pregnancies carried to term. Recovery of any organism from the amniotic cavity was strongly associated with chorioamnionitis confirmed by histology. Comparison of the rates of indicating placental infection found in this study and a study performed between 1981 and 1983, showed that the program aiming at detection and treatment of silent intrauterine infection has only partially been successful.

摘要

对1995年至1998年期间发生的984例妊娠(758例足月妊娠和226例早产妊娠)的胎盘组织学进行了研究,并在918例剖宫产术中采集了羊膜腔培养物。组织学检查显示,20.3%的胎盘存在胎盘感染。758例足月妊娠中有119例(15.7%)确诊为绒毛膜羊膜炎,而226例早产妊娠中有81例(35.8%);差异具有高度显著性(卡方=26.6,p<0.01)。细菌学培养结果显示,所有病例中有19.7%(181/918)出现细菌生长,早产中的发生率(54/133,40.3%,卡方=25.2,p<0.01)显著高于足月妊娠。从羊膜腔中分离出任何微生物都与组织学确诊的绒毛膜羊膜炎密切相关。将本研究中发现的胎盘感染指示率与1981年至1983年期间进行的一项研究进行比较,结果表明,旨在检测和治疗隐匿性宫内感染的方案仅部分取得成功。

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