Chaturvedi C M, Chowdhary A, Wall P T, Koike T I, Cornett L E
Department of Zoology, Banaras Hindu University, Varanasi, 221 005, India.
Gen Comp Endocrinol. 2000 Jan;117(1):129-37. doi: 10.1006/gcen.1999.7400.
To examine a possible sexual dimorphism in the osmotic control of arginine vasotocin (AVT) release in birds, age-matched male and female Japanese quail were subjected to water deprivation. The observed increased plasma osmolalities were accompanied by increased plasma AVT levels. Plasma mesotocin levels did not change with water deprivation. The sensitivity of the osmotic control of AVT release as determined by the slope of the relationship between plasma AVT levels and plasma osmolalities was significantly (P < 0.05) higher in males than in females. By Northern blot analysis, levels of hypothalamic AVT gene transcripts were increased 2.3 +/- 0.14- and 3.5 +/- 0.13-fold in water-deprived male and female Japanese quail, respectively, compared to normally hydrated birds. Our data suggest gender-related differences in the osmotic control of AVT release and in hypothalamic AVT gene expression in the Japanese quail.
为研究鸟类中精氨酸血管加压素（AVT）释放的渗透调节中可能存在的性别差异，对年龄匹配的雄性和雌性日本鹌鹑进行了脱水处理。观察到血浆渗透压升高的同时，血浆AVT水平也升高。血浆中促黑激素水平并未因脱水而改变。通过血浆AVT水平与血浆渗透压之间关系的斜率确定，AVT释放的渗透调节敏感性在雄性中显著（P < 0.05）高于雌性。通过Northern印迹分析，与正常饮水的鹌鹑相比，脱水的雄性和雌性日本鹌鹑下丘脑AVT基因转录本水平分别增加了2.3 +/- 0.14倍和3.5 +/- 0.13倍。我们的数据表明，日本鹌鹑在AVT释放的渗透调节和下丘脑AVT基因表达方面存在与性别相关的差异。
