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分娩时硬膜外镇痛应用某些方面的最新进展。

Update on some aspects of the use of epidural analgesia in labour.

作者信息

Okojie P, Cook P

机构信息

Women's Centre, John Radcliffe Hospital, Oxford, UK.

出版信息

Int J Clin Pract. 1999 Sep;53(6):418-20.

Abstract

The aim of the study was to investigate the effect of epidural analgesia on blood pressure, duration of the second stage and mode of delivery. In a prospective controlled study carried out in a district general hospital, 122 parturients made up the study population; 81 had epidural blocks and 41 had other forms of analgesia during labour. Data were collated using questionnaires within 48 hours of delivery: 58/81 (71.6%) of those who chose epidural were primigravidae compared with 14/41 (34%) in the non-epidural group (p < 0.001). During labour, minimum diastolic blood pressure was significantly lower in the epidural group: 65.8 versus 72.4 mmHg (p = 0.003). Mean duration of the second stage of labour was significantly longer in the epidural group: 108.3 versus 41.6 minutes (p < 0.0001); 28/81 (34.6%) of the epidural group had operative vaginal deliveries compared with 6/41 (14.6%) of the non-epidural group (p = 0.0004). Epidural analgesia provides an effective form of pain relief in labour, which has a particularly strong appeal to primigravidae. It has a hypotensive effect which can be put to beneficial effect in hypertensive disease of pregnancy, but is significantly associated with a lengthened second stage of labour, resulting in an increased operative vaginal delivery rate.

摘要

本研究的目的是调查硬膜外镇痛对血压、第二产程时长及分娩方式的影响。在一家地区综合医院进行的一项前瞻性对照研究中,122名产妇构成了研究人群;81名产妇在分娩期间接受了硬膜外阻滞,41名产妇接受了其他形式的镇痛。在分娩后48小时内使用问卷收集数据:选择硬膜外镇痛的产妇中,58/81(71.6%)为初产妇,而非硬膜外组为14/41(34%)(p<0.001)。分娩期间,硬膜外组的最低舒张压显著更低:65.8 mmHg 对比 72.4 mmHg(p = 0.003)。硬膜外组第二产程的平均时长显著更长:108.3分钟对比41.6分钟(p<0.0001);硬膜外组28/81(34.6%)进行了阴道助产,而非硬膜外组为6/41(14.6%)(p = 0.0004)。硬膜外镇痛是分娩时一种有效的镇痛方式,对初产妇尤其有吸引力。它有降压作用,这在妊娠高血压疾病中可产生有益效果,但与第二产程延长显著相关,导致阴道助产率增加。

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