Bodner-Adler B, Bodner K, Kimberger O, Wagenbichler P, Kaider A, Husslein P, Mayerhofer K
Department of Gynaecology, University of Vienna Medical School, Währinger Gürtel 18-20, A-1090 Vienna, Austria.
Arch Gynecol Obstet. 2002 Dec;267(2):81-4. doi: 10.1007/s00404-001-0280-5.
The aim of this study was to determine if epidural analgesia is associated with increased risk of obstetric lacerations during spontaneous vaginal delivery. Furthermore we assessed the effect of epidural analgesia on maternal and neonatal parameters. This multicenter study consisted of an analysis of data from the delivery databases of the University Hospital of Vienna and the Semmelweis Women's Hospital Vienna. This study was restricted to a sample that included all women with uncomplicated pregnancy, a gestational age >37(th) weeks and a pregnancy with cephalic presentation. Epidural analgesia was set during the first stage of labour. Techniques and management styles of epidural analgesia were the same in both hospitals. No statistically significant association was found between epidural analgesia and the occurrence of perineal tears (p=0.83), vaginal (p=0.37) or labial trauma (p=0.11). Furthermore the results demonstrated a statistically significant higher rate of primiparous women using epidural analgesia (p=0.001). A statistically significant prolonged second stage of labour was observed in women undergoing epidural analgesia (p=0.0001). Episiotomy was statistically significant more frequent in women requiring epidural analgesia (p=0.0001). Women who were treated with epidural analgesia were more likely to have labour augmented with oxytocin (p=0.001). No statistically significant differences in neonatal outcomes determined by APGAR score (p=0.84) and cord pH (p=0.23) were observed between the two groups. Women undergoing epidural analgesia demonstrated a prolonged second stage of labour, a higher rate of episiotomy and an increased use of oxytocin to augment labour. Some of these adverse effects might be caused by the higher rate of primiparous women using epidural analgesia. However, epidural analgesia showed no evidence of a detrimental effect on the integrity of the birth-canal in spontaneous vaginal delivery. In our opinion it is a save and effective method of pain relief during labour.
本研究的目的是确定硬膜外镇痛是否与自然阴道分娩时产科裂伤风险增加相关。此外,我们评估了硬膜外镇痛对母体和新生儿参数的影响。这项多中心研究包括对维也纳大学医院和维也纳塞梅尔维斯妇女医院分娩数据库中的数据进行分析。本研究仅限于一个样本,该样本包括所有妊娠无并发症、孕周>37周且为头位妊娠的妇女。硬膜外镇痛在第一产程期间实施。两家医院硬膜外镇痛的技术和管理方式相同。未发现硬膜外镇痛与会阴撕裂(p=0.83)、阴道(p=0.37)或阴唇创伤(p=0.11)的发生之间存在统计学上的显著关联。此外,结果显示使用硬膜外镇痛的初产妇比例在统计学上显著更高(p=0.001)。在接受硬膜外镇痛的妇女中观察到第二产程在统计学上显著延长(p=0.0001)。在需要硬膜外镇痛的妇女中,会阴切开术在统计学上显著更频繁(p=0.0001)。接受硬膜外镇痛治疗的妇女更有可能使用缩宫素加强宫缩(p=0.001)。两组之间在通过阿氏评分(p=0.84)和脐血pH值(p=0.23)确定的新生儿结局方面未观察到统计学上的显著差异。接受硬膜外镇痛的妇女表现出第二产程延长、会阴切开术比例更高以及使用缩宫素加强宫缩的情况增加。其中一些不良影响可能是由于使用硬膜外镇痛的初产妇比例较高所致。然而,硬膜外镇痛未显示出对自然阴道分娩时产道完整性有有害影响的证据。我们认为它是分娩期间一种安全有效的镇痛方法。