Katz A, Gvaryahu G, Robinzon B, Snapir N, Barnea A
The Hebrew University of Jerusalem, Faculty of Agricultural, Food and Environmental Quality Sciences, Department of Animal Science, Rehovot, Israel.
Poult Sci. 1999 Dec;78(12):1786-9. doi: 10.1093/ps/78.12.1786.
Embryonic and posthatch long-term exposure to the odor of 2-methoxy-3-isobutyl-pyrazine (2M3IP) was examined for its potential physiological consequences as reflected in changes in BW and organ weights in domestic chicks (Gallus gallus domesticus). Experiments were run from Day 1 of incubation to the age of 3 wk with a total of 360 fertile chicken eggs. The experimental design consisted of four treatment groups: PP chicks were exposed to 2M3IP during both incubation and posthatch rearing; PC chicks were exposed to 2M3IP during incubation only; CP chicks were exposed to 2M3IP during rearing period only; CC control chicks were not exposed to 2M3IP. Chicks were weighed immediately after hatch and at 3 wk of age, when they were necropsied. Various organs (thyroid, adrenal, testes, comb, liver, spleen, abdominal fat, and the bursa of Fabricius) were removed and weighed. Body weights of both sexes in the PP group were reduced. This reduction was significant in males relative to both CP and CC groups and in females only relative to the CP group. Effects of 2M3IP exposure on the examined organs were as follows: in males, adrenal gland weight significantly increased in the PP group vs all other groups. No weight differences were found between the other inspected organs among the four treatments. In females, comb weight significantly decreased compared with the rest of the groups when 2M3IP exposure occurred during incubation (PC). Further investigation is needed to study the mechanisms that underlie the differential effects of pyrazine odor on male and female chicks.
研究了胚胎期和孵化后长期暴露于2-甲氧基-3-异丁基吡嗪（2M3IP）气味对家鸡（Gallus gallus domesticus）体重和器官重量变化所反映的潜在生理影响。实验从孵化第1天开始，持续到3周龄，共有360枚受精鸡蛋。实验设计包括四个处理组：PP组雏鸡在孵化期和孵化后饲养期都暴露于2M3IP；PC组雏鸡仅在孵化期暴露于2M3IP；CP组雏鸡仅在饲养期暴露于2M3IP；CC组对照雏鸡不暴露于2M3IP。雏鸡在孵化后和3周龄尸检时立即称重。取出并称重各种器官（甲状腺、肾上腺、睾丸、鸡冠、肝脏、脾脏、腹部脂肪和法氏囊）。PP组两性的体重均降低。相对于CP组和CC组，雄性体重降低显著，而雌性仅相对于CP组体重降低显著。2M3IP暴露对所检查器官的影响如下：在雄性中，PP组的肾上腺重量相对于所有其他组显著增加。四种处理之间其他检查器官的重量没有差异。在雌性中，当在孵化期（PC组）暴露于2M3IP时，鸡冠重量与其他组相比显著降低。需要进一步研究以探讨吡嗪气味对雄性和雌性雏鸡产生不同影响的潜在机制。
