Onercl M, Yilmaz T, Gedikoğlu G
Departments of Otolaryngology-Head and Neck Surgery, Hacettepe University Faculty of Medicine, Ankara, Turkey.
Otolaryngol Head Neck Surg. 2000 Jan;122(1):139-42. doi: 10.1016/S0194-5998(00)70162-8.
Tumor thickness is a relatively new prognostic factor that has been investigated for lower lip cancer. This study was performed in 27 patients, 13 of whom had histopathologically confirmed cervical metastasis, to investigate whether tumor thickness could be used as a predictor of cervical lymph node metastasis. The mean tumor thickness of those cases with neck metastasis was 5.60 mm (SD = 2.24), and the mean thickness of cases without neck metastasis was 3. 79 mm (SD = 1.68). The difference between tumor thicknesses of both groups was found to be statistically significant (P < 0.05). The tumor thickness of 5 mm was determined as a cutoff point, above which the cervical lymph node metastasis rate was significantly increased. As a conclusion, tumor thickness is an objective histopathologic factor that is easily reproducible; it significantly influences cervical lymph node metastasis in lower lip cancer, and it may be used in the assessment of prognosis.
肿瘤厚度是一个相对较新的用于评估下唇癌预后的因素。本研究纳入了27例患者，其中13例经组织病理学证实有颈部转移，旨在探究肿瘤厚度是否可作为颈部淋巴结转移的预测指标。有颈部转移的病例的平均肿瘤厚度为5.60毫米（标准差=2.24），无颈部转移的病例的平均厚度为3.79毫米（标准差=1.68）。两组的肿瘤厚度差异具有统计学意义（P<0.05）。将5毫米的肿瘤厚度确定为一个分界点，高于此分界点，颈部淋巴结转移率显著增加。总之，肿瘤厚度是一个易于重现的客观组织病理学因素；它对下唇癌的颈部淋巴结转移有显著影响，可用于预后评估。
