Limin S, Jarvie D R, Chick J, Simpson D
Department of Psychiatry, University of Edinburgh, Royal Edinburgh Hospital.
Scott Med J. 1999 Oct;44(5):140-2. doi: 10.1177/003693309904400505.
Biochemical markers of alcohol consumption are useful for the detection and monitoring of problem drinking. Blood samples from 37 patients attending an alcohol treatment clinic were analysed for GGT and %CDT, and results were compared with self-reported periods of abstinence and alcohol consumption. Poor correlation was obtained between GGT and %CDT, and between these assays and self-reported alcohol use. The apparent sensitivity and specificity of GGT (57%, 63%) and %CDT (43%, 88%), were considerably lower than those reported by other workers.
酒精摄入的生化标志物有助于检测和监测问题饮酒情况。对37名前往酒精治疗诊所就诊的患者的血样进行了γ-谷氨酰转移酶(GGT)和%CDT分析,并将结果与自我报告的戒酒期和酒精摄入量进行了比较。GGT与%CDT之间以及这些检测与自我报告的酒精使用情况之间的相关性较差。GGT(57%,63%)和%CDT(43%,88%)的表观敏感性和特异性明显低于其他研究人员报告的数值。