Parrish T
Department of Radiology and Biomedical Engineering, Northwestern University, Chicago, Illinois, USA.
Magn Reson Imaging Clin N Am. 1999 Nov;7(4):765-82, vi.
Functional MR (fMR) imaging offers unprecedented spatial and temporal resolution of brain cognition. The impact of this technology on neuroscience research is just now being explored. This article discusses blood oxygenation level-dependent-based fMR imaging. Topics include the origin of the MR-based signal, data acquisition and sequence dependence, and paradigm design issues--issues that need to be fully understood to properly design and interpret the fMR imaging experiment.
功能磁共振(fMR)成像提供了前所未有的大脑认知空间和时间分辨率。这项技术对神经科学研究的影响刚刚开始被探索。本文讨论基于血氧水平依赖的fMR成像。主题包括基于磁共振的信号起源、数据采集和序列依赖性,以及范式设计问题——这些问题需要被充分理解,以便正确设计和解释fMR成像实验。