Brugnami F, Mellonig J T
Department of Periodontology, Tufts University School of Dental Medicine, Boston, Massachusetts, USA.
Int J Periodontics Restorative Dent. 1999 Jun;19(3):243-9.
Following endodontic treatment, a large periapical lesion (9.0 mm x 9.0 mm) at a maxillary central incisor was treated with demineralized freeze-dried bone allograft (DFDBA) using the principles of guided tissue regeneration. The physical barrier was removed 6 months postsurgical. The cortical alveolar plate was observed to be completely reconstructed. Histologic evaluation demonstrated lamellar bone surrounding DFDBA particles. Radiographic follow-up 1 year posttreatment demonstrated complete resolution of the periapical radiolucency.
根管治疗后，对上颌中切牙处一个较大的根尖周病变（9.0毫米×9.0毫米）采用引导组织再生原理，使用脱矿冻干骨同种异体移植物（DFDBA）进行治疗。术后6个月拆除物理屏障。观察到牙槽骨皮质板已完全重建。组织学评估显示DFDBA颗粒周围有板层骨。治疗后1年的影像学随访显示根尖周透射区已完全消失。
