Dubey P K, Singh A K
Department of Anesthesiology, Indira Gandhi Institute of Medical Sciences, Patna, India.
J Neurosurg Anesthesiol. 2000 Jan;12(1):54-6. doi: 10.1097/00008506-200001000-00011.
Hazards of application of hydrogen peroxide to semiclosed space are well known. We present a case of suspected gas embolism following hydrogen peroxide irrigation of the surgical field during posterior fossa surgery in the prone position. Severe cardiovascular collapse occurred when the wound was irrigated with hydrogen peroxide solution. Generation of pressure gradient leads to absorption of a considerable amount of oxygen giving rise to features of venous gas embolism. Although the case was associated with an uneventful recovery, use of hydrogen peroxide for securing hemostasis should be avoided.
过氧化氢应用于半封闭空间的危害是众所周知的。我们报告一例在俯卧位后颅窝手术期间用双氧水溶液冲洗手术野后疑似气体栓塞的病例。在用过氧化氢溶液冲洗伤口时发生了严重的心血管衰竭。压力梯度的产生导致大量氧气吸收，引发静脉气体栓塞的特征。尽管该病例最终顺利康复，但应避免使用过氧化氢来止血。
