福氏志贺氏菌中的血清型转换噬菌体与O抗原修饰
Serotype-converting bacteriophages and O-antigen modification in Shigella flexneri.
作者信息
Allison G E, Verma N K
机构信息
Divn of Biochemistry and Molecular Biology, Faculty of Science, Australian National University, Canberra, ACT, 0200, Australia.
出版信息
Trends Microbiol. 2000 Jan;8(1):17-23. doi: 10.1016/s0966-842x(99)01646-7.
Abstract
O-antigen modification (serotype conversion) in Shigella flexneri, which is an important virulence determinant, is conferred by temperate bacteriophages. Several serotype-converting phages have been isolated and preliminary characterization has identified the genes involved in O-antigen modification, and has also provided insight into the molecular biology of these phages.
摘要
宋内志贺菌中的O抗原修饰（血清型转换）是一种重要的毒力决定因素，由温和噬菌体赋予。几种血清型转换噬菌体已被分离出来，初步表征已确定了参与O抗原修饰的基因，并且还深入了解了这些噬菌体的分子生物学。
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