Herbaczyńska-Cedro K
Cardiovascular Laboratory, Research Centre of Experimental & Clinical Medicine, Polish Academy of Sciences, Warsaw.
J Physiol Pharmacol. 1999 Dec;50(4):653-60.
The author reviews controlled clinical investigation on the effectiveness of L-arginine in cardiovascular diseases. Positive results were observed in hyperlipidemic subjects and in patients with a critical stage of the peripheral arterial occlusive disease. Patients with stable ischemic heart disease responded to L-arginine to some extent, while results of L-arginine therapy in congestive heart failure are inconsistent. Null effects if L-arginine has been documented in essential hypertension.
作者回顾了关于L-精氨酸在心血管疾病中有效性的对照临床研究。在高脂血症患者和外周动脉闭塞病关键阶段的患者中观察到了阳性结果。稳定型缺血性心脏病患者对L-精氨酸有一定反应,而L-精氨酸治疗充血性心力衰竭的结果并不一致。在原发性高血压中,L-精氨酸已被证明无效果。