Moeller H C, Heiland M, Vesper M, Hellner D, Schmelzle R
Abteilung für Mund-, Kiefer- und Gesichtschirurgie, Universität Hamburg-Eppendorf.
Mund Kiefer Gesichtschir. 1999 Nov;3(6):331-4. doi: 10.1007/s100060050166.
We present the case of a primary solitary malignant schwannoma of the trigeminal nerve. A total of 55 cases have been described in the literature; however, in these cases two tumors were affecting the supraorbital branch. This nerve-sheath tumor usually affects men in the fifth decade of life. The main clinical sign of malignant schwannomas of the head and neck is an indolent swelling. Hematogenic or lymphogenic metastasis has not been described. Because of the pleomorphism of the tumor cells immunohistochemical study is important. The treatment of choice is radical resection, possibly with adjuvant radio- or chemotherapy. The 5-year survival rate of malignant schwannoma of the trigeminal nerve is 41.7%.
我们报告一例原发性三叉神经孤立性恶性神经鞘瘤。文献中总共描述了55例；然而，在这些病例中，有两例肿瘤累及眶上支。这种神经鞘瘤通常影响50岁左右的男性。头颈部恶性神经鞘瘤的主要临床体征是无痛性肿胀。尚未见血行或淋巴转移的报道。由于肿瘤细胞的多形性，免疫组化研究很重要。首选治疗方法是根治性切除，可能需辅助放疗或化疗。三叉神经恶性神经鞘瘤的5年生存率为41.7%。
