Berdysheva L V, Kichikulova T P, Manukhin B N
N. K. Koltsov Institute of Developmental Biology of the Russian Acad Sci., Moscow, Russia.
Ross Fiziol Zh Im I M Sechenova. 1999 Aug;85(8):1090-4.
In the prostatic half of the rat vas deferens, the response to noradrenaline under the cocaine effect revealed a phasic and a tonic components, whereas in the epididymal portion of the vas deferens there only occurred the tonic component. Cocaine increased the maximal tonic contractile response to noradrenaline in the epididymal portion and the maximal phasic response--in the prostatic one. Mechanisms of direct postsynaptic action of cocaine are discussed.
在大鼠输精管前列腺段，可卡因作用下对去甲肾上腺素的反应呈现出一个时相性和一个紧张性成分，而在输精管附睾段仅出现紧张性成分。可卡因增加了附睾段对去甲肾上腺素的最大紧张性收缩反应以及前列腺段的最大时相性反应。文中讨论了可卡因直接突触后作用的机制。
