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台湾老年人血清尿酸与心血管危险因素之间的关联。

Association between serum uric acid and cardiovascular risk factors among elderly people in Taiwan.

作者信息

Lai S W, Li T C, Li C I, Tan C K, Ng K C, Lai M M, Liu C S, Lin C C

机构信息

Department of Community Medicine, China Medical College Hospital, Taichung, Taiwan, Republic of China.

出版信息

Kaohsiung J Med Sci. 1999 Dec;15(12):686-90.

Abstract

In order to understand the distribution of serum uric acid and the relationship between serum uric acid and the cardiovascular risk factor among elderly people, a cross-sectional study was conducted in Chung-Shing-Shin-Tseun community in Taiwan in May 1998. All individuals aged 65 and over were collected. A total of 1123 persons, out of 1774 registered residents, were contacted by face-to-face interview. The response rate was 63.3%. However, only 586 respondents had blood tests and completed questionnaires. Analysis in this study was based on these 586 subjects. The mean uric acid values were 7.4 +/- 1.8 mg/dl in men and 6.3 +/- 1.6 mg/dl in women, respectively (p < 0.001). Multivariate linear regression showed that serum uric acid was significantly correlated with sex and body mass index. Simple correlation showed that serum uric acid was significantly correlated with diastolic pressure, total cholesterol, triglyceride and creatinine. Age, systolic pressure and fasting glucose were not related to serum uric acid. In our conclusion, the uric acid values are high among elderly people. The serum uric acid levels are significantly associated with the cardiovascular risk factors among elderly people.

摘要

为了解台湾地区老年人血清尿酸的分布情况以及血清尿酸与心血管危险因素之间的关系,1998年5月在台湾中兴新村社区进行了一项横断面研究。收集了所有65岁及以上的个体。在1774名登记居民中,共有1123人接受了面对面访谈。应答率为63.3%。然而,只有586名受访者进行了血液检测并完成了问卷调查。本研究的分析基于这586名受试者。男性的平均尿酸值为7.4±1.8mg/dl,女性为6.3±1.6mg/dl(p<0.001)。多变量线性回归显示血清尿酸与性别和体重指数显著相关。简单相关性分析显示血清尿酸与舒张压、总胆固醇、甘油三酯和肌酐显著相关。年龄、收缩压和空腹血糖与血清尿酸无关。我们的结论是,老年人的尿酸值较高。老年人的血清尿酸水平与心血管危险因素显著相关。

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