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[alpha-Neurotoxins and alpha-conotoxins--nicotinic cholinoreceptor blockers].

作者信息

Utkin Iu N, Kasheverov I E, Tsetlin V I

机构信息

Shemyakin-Ovchinnikov Institute of Bioorganic Chemistry, Russian Academy of Sciences, Moscow, Russia.

出版信息

Bioorg Khim. 1999 Nov;25(11):805-10.

Abstract

The review is devoted to the competitive blockers of different nicotinic acetylcholine receptors, alpha-neurotoxins from snake venoms, and alpha-conotoxins from marine snails of the Conidae family. The relationship between the structure and function of these toxins is discussed. Recent data on the mechanism of alpha-neurotoxin and alpha-conotoxin interaction with the nicotinic acetylcholine receptor are presented.

摘要

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