Suppr超能文献

白内障手术的联合镇静和局部麻醉

Combined sedation and topical anesthesia for cataract surgery.

作者信息

Harman D M

机构信息

Harman Eye Center, Forest, Virginia 24551, USA.

出版信息

J Cataract Refract Surg. 2000 Jan;26(1):109-13. doi: 10.1016/s0886-3350(99)00330-2.

Abstract

PURPOSE

To determine whether lidocaine jelly is as efficacious as tetracaine drops for obtaining ocular anesthesia and to evaluate sublingual lorazepam as premedication for sedation in cataract surgery.

SETTING

An ambulatory surgical center dedicated to ophthalmic surgery.

METHODS

The study was divided into 2 phases. In the first, 100 patients were divided into 2 groups of 50 each. The first group received tetracaine 0.5% drops for anesthesia. The second group received lidocaine 2% jelly for topical anesthesia. In the second stage, 100 patients were divided into 2 groups of 50 each. The first 50 patients were given 1 mg of sublingual lorazepam before surgery. The second group had cataract surgery without sublingual lorazepam. All patients were operated on by the same surgeon in an ambulatory surgical center. The technique was temporal clear corneal cataract surgery with foldable intraocular lens implantation. Exclusions from the study were the need to convert to peribulbar or retrobulbar anesthesia, intraocular complications, and altered mental status.

RESULTS

In the first phase of the study, lidocaine 2% jelly was as efficacious as tetracaine 0.5% drops for topical anesthesia in cataract surgery. In the second phase of the study, overall, patients in the lorazepam group had less anxiety, greater amnesia, and lower blood pressure than those not receiving lorazepam as sedation for topical anesthesia.

CONCLUSIONS

Lidocaine 2% jelly combined with sublingual lorazepam provided excellent cost-effective anesthesia and sedation for topical anesthesia in cataract surgery and enhanced patient satisfaction with the procedure.

摘要

目的

确定利多卡因凝胶在获得眼部麻醉方面是否与丁卡因滴眼液同样有效,并评估舌下含服劳拉西泮作为白内障手术镇静预处理药物的效果。

地点

一家专门进行眼科手术的门诊手术中心。

方法

该研究分为两个阶段。在第一阶段,100名患者被分为两组,每组50人。第一组接受0.5%丁卡因滴眼液麻醉。第二组接受2%利多卡因凝胶局部麻醉。在第二阶段,100名患者也被分为两组,每组50人。前50名患者在手术前给予1毫克舌下含服劳拉西泮。第二组在无舌下含服劳拉西泮的情况下进行白内障手术。所有患者均在门诊手术中心由同一位外科医生进行手术。手术技术为颞侧透明角膜白内障手术并植入可折叠人工晶状体。排除标准为需要转为球周或球后麻醉、眼内并发症以及精神状态改变。

结果

在研究的第一阶段,2%利多卡因凝胶在白内障手术局部麻醉方面与0.5%丁卡因滴眼液同样有效。在研究的第二阶段,总体而言,劳拉西泮组患者在作为局部麻醉镇静用药时,比未接受劳拉西泮的患者焦虑程度更低、遗忘效果更好且血压更低。

结论

2%利多卡因凝胶联合舌下含服劳拉西泮为白内障手术局部麻醉提供了性价比高的麻醉和镇静效果,并提高了患者对手术过程的满意度。

文献AI研究员

20分钟写一篇综述,助力文献阅读效率提升50倍。

立即体验

用中文搜PubMed

大模型驱动的PubMed中文搜索引擎

马上搜索

文档翻译

学术文献翻译模型,支持多种主流文档格式。

立即体验