Albert T J, Pinto M, Denis F
Rothman Institute, Philadelphia, Pennsylvania, USA.
Spine (Phila Pa 1976). 2000 Jan;25(1):123-9; discussion 130. doi: 10.1097/00007632-200001010-00021.
An independent retrospective review of 37 patients undergoing 39 anteroposterior lumbar fusions for lumbar pseudarthrosis repair between 1984 and 1990.
To evaluate radiographically and functionally the results of the combined anteroposterior fusion for the management of symptomatic lumbar pseudarthrosis, and to assess risk factors for functional failure after the procedure.
Most reported techniques of pseudarthrosis repair involve posterior fusion with no instrumentation, posterior fusion with instrumentation, or anterior fusion alone. The results of lumbar pseudarthrosis repair are poor. Fusion rates range from 30% to 70%, with only a 30% to 50% rate of functional success.
Thirty-nine procedures were assessed in 37 patients. The outcomes were assessed radiographically (solid fusion vs. pseudarthrosis) and functionally (success vs. failure). Radiographs were assessed at follow-up examination for consolidation of fusion anteriorly and posteriorly. Functional outcome was graded by using multiple instruments, including data from chart review and the follow-up outcome questionnaire. A functional failure score that took into account 10 items was developed.
In this patient population (37 patients, 59% with a smoking history, 71% with compensation or legal claims), there was a 10% pseudarthrosis rate. Pseudarthrosis was defined when one or more levels were involved and when it occurred anteriorly and posteriorly. In 12 patients (35%), the outcome was rated as functional failure. The presence of one or more abnormal neurologic findings and significant narcotic use before surgery significantly increased the chance of a patient's outcome being functional failure. Workmen's Compensation or legal status before surgery also increased the chance of functional failure, though this correlation was not statistically significant.
A combined anterior and posterior approach for the management of symptomatic lumbar pseudarthrosis is a viable alternative to posterior fusion alone. In fact, this procedure affords a higher fusion rate based on radiographic assessment. Functional failure rates may be decreased by using caution for those patients using narcotics regularly before surgery or in those with unexplained preoperative neurologic abnormal findings.
对1984年至1990年间接受39例前后路腰椎融合术修复腰椎假关节的37例患者进行独立回顾性研究。
通过影像学和功能评估前后路联合融合治疗有症状腰椎假关节的效果,并评估该手术后功能失败的危险因素。
大多数报道的假关节修复技术包括单纯后路融合无内固定、后路融合加内固定或单纯前路融合。腰椎假关节修复的效果较差。融合率在30%至70%之间,功能成功率仅为30%至50%。
对37例患者的39例手术进行评估。通过影像学(坚固融合与假关节)和功能(成功与失败)评估结果。在随访检查时评估X线片以观察前后路融合的巩固情况。使用多种工具对功能结果进行分级,包括病历审查数据和随访结果问卷。制定了一个考虑10项内容的功能失败评分。
在该患者群体(37例患者,59%有吸烟史,71%有赔偿或法律索赔)中,假关节发生率为10%。当累及一个或多个节段且前后路均发生假关节时定义为假关节。12例患者(35%)的结果被评为功能失败。术前存在一项或多项异常神经学表现以及大量使用麻醉剂显著增加了患者功能失败的可能性。术前的工伤赔偿或法律状况也增加了功能失败的可能性,尽管这种相关性无统计学意义。
对于有症状的腰椎假关节,前后路联合手术是单纯后路融合的可行替代方法。事实上,根据影像学评估,该手术能提供更高的融合率。对于术前经常使用麻醉剂的患者或术前有无法解释的神经学异常表现的患者,谨慎操作可能会降低功能失败率。