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球后注射用于后段手术的局部麻醉。

Sub-Tenon's injection for local anesthesia in posterior segment surgery.

作者信息

Li H K, Abouleish A, Grady J, Groeschel W, Gill K S

机构信息

Department of Ophthalmology and Visual Sciences, University of Texas Medical Branch, Galveston 77555-0787, USA.

出版信息

Ophthalmology. 2000 Jan;107(1):41-6; discussion 46-7. doi: 10.1016/s0161-6420(99)00009-3.

Abstract

OBJECTIVE

To determine whether the sub-Tenon's parabulbar approach for local anesthesia is a safe and effective choice for posterior segment surgery.

DESIGN

Prospective, noncomparative case series.

PARTICIPANTS

Two hundred seventy-six consecutive patients underwent posterior segment surgery at the University of Texas Medical Branch.

INTERVENTION

Two hundred patients received sub-Tenon's parabulbar anesthesia containing an 11 -ml mixture of 5-ml 2% lidocaine (Xylocaine), 5-ml 0.5% bupivacaine (Marcaine), and 1 ml of 150 hyaluronidase (Wydase) units as primary anesthesia. The method did not involve a separate transcutaneous lid nerve or subconjunctival injection.

MAIN OUTCOME MEASURES

The proportion of cases receiving supplementation (significant intravenous anesthesia, intraoperative local anesthesia, or both) was estimated. Its relationship to duration of surgery and surgical procedures deemed painful was assessed. Surgery lasting 3 hours or more was considered a long duration. Both scleral buckle and cryotherapy were considered painful procedures. The proportion of cases receiving additional local anesthesia preoperatively was also evaluated. Complications associated with sub-Tenon's parabulbar injection were monitored.

RESULTS

There were 101 instances of patients receiving additional anesthesia. Nineteen received additional preoperative sub-Tenon's anesthesia, 12 received intraoperative local anesthesia supplementation, and 70 received intravenous medication. Of these 70, 19 required what the authors defined as a significant amount of intravenous medication, three of whom also received intraoperative local anesthesia supplementation. Consequently, 28 of 200 patients (14%; 95% confidence interval: 9.5, 19.6) received supplementation (significant intravenous anesthesia, intraoperative local anesthesia, or both). The proportion of cases receiving supplementation was directly related to duration of surgery. Patients involved in longer cases (51.7% vs. 7.6%; P < 0.001) and those involved in more painful procedures (48.2% vs. 8.7%; P < 0.001) were more likely to receive supplementation. Adjusting for surgery duration, a greater proportion of patients undergoing painful procedures required supplementation (31.3% vs. 0.5% for surgery < 3 hours, P = 0.003; 72.7% vs. 38.9% for surgery > or = 3 hours, P = 0.13). No associated ocular or systemic complications were observed.

CONCLUSIONS

The results of this large study demonstrate that a single injection of sub-Tenon's anesthesia is relatively safe and effective for achieving local anesthesia during vitrectomies, with or without other intraocular procedures, lasting less than 3 hours. Other types of posterior segment surgery may require supplementation if they are more painful procedures, such as scleral buckle or cryotherapy, or last longer than 3 hours.

摘要

目的

确定球后Tenon囊下局部麻醉方法对于后节手术是否是一种安全有效的选择。

设计

前瞻性、非对照病例系列研究。

研究对象

276例连续在德克萨斯大学医学分校接受后节手术的患者。

干预措施

200例患者接受球后Tenon囊下麻醉,麻醉药为11毫升混合液,其中含5毫升2%利多卡因(赛罗卡因)、5毫升0.5%布比卡因(耐乐品)及1毫升150单位透明质酸酶(玻璃糖醛酸酶)作为主要麻醉方式。该方法无需单独进行经皮睑神经或结膜下注射。

主要观察指标

评估接受补充麻醉(深度静脉麻醉、术中局部麻醉或两者皆用)的病例比例。评估其与手术时长及被认为疼痛的手术操作之间的关系。手术持续3小时或更长时间被视为长时手术。巩膜扣带术和冷冻疗法均被视为疼痛操作。还评估了术前接受额外局部麻醉的病例比例。监测与球后Tenon囊下注射相关的并发症。

结果

有101例患者接受了额外麻醉。19例接受了术前额外的球后Tenon囊下麻醉,12例接受了术中局部麻醉补充,70例接受了静脉用药。在这70例中,19例需要作者定义的大量静脉用药,其中3例还接受了术中局部麻醉补充。因此,200例患者中有28例(14%;95%置信区间:9.5,19.6)接受了补充麻醉(深度静脉麻醉、术中局部麻醉或两者皆用)。接受补充麻醉的病例比例与手术时长直接相关。手术时间较长的患者(51.7%对7.6%;P<0.001)以及接受更疼痛手术操作的患者(48.2%对8.7%;P<0.001)更有可能接受补充麻醉。校正手术时长后,接受疼痛手术操作的患者中需要补充麻醉的比例更高(手术时间<3小时的患者为31.3%对0.5%,P = 0.003;手术时间≥3小时的患者为72.7%对38.9%,P = 0.13)。未观察到相关的眼部或全身并发症。

结论

这项大型研究结果表明,对于持续时间少于3小时的玻璃体切除术,无论是否联合其他眼内手术,单次球后Tenon囊下麻醉在实现局部麻醉方面相对安全有效。如果其他类型的后节手术操作更疼痛,如巩膜扣带术或冷冻疗法,或手术持续时间超过3小时,则可能需要补充麻醉。

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