Ruzicka F, Pawlowsky J, Erber A
Osterr Z Onkol. 1975;2(6):157-66.
By means of electron microscopy, myeloblasts with spontaneous radial segmentation of the nuclei from a patient with micromegakaryotic chronic myelosis in the blastic crisis were analysed. The centriol was found in the center of the cells and microtubules were found between the segments of the nucleus. These observations support the hypothesis that spontaneous radial segmentations of the nuclei of tumor cells is associated with a contractile process of the microtubules with split the nucleus.
通过电子显微镜,对一名处于原始细胞危象的微巨核细胞慢性骨髓增殖性肿瘤患者的具有自发核放射状分割的原始粒细胞进行了分析。在细胞中心发现了中心粒,并且在细胞核的各节段之间发现了微管。这些观察结果支持这样的假说,即肿瘤细胞核的自发放射状分割与使细胞核分裂的微管收缩过程有关。