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Localization of mRNA for SHIP2, SH2 domain-containing inositol polyphosphate 5-phosphatase, in the brain of developing and mature rats.

作者信息

Kudo M, Saito S, Owada Y, Suzaki H, Kondo H

机构信息

Division of Histology, Department of Cell Biology, Graduate School of Medical Science, Tohoku University, 2-1, Seiryo-machi, Aoba-ku, Sendai, Japan.

出版信息

Brain Res Mol Brain Res. 2000 Jan 10;75(1):172-7. doi: 10.1016/s0169-328x(99)00311-3.

DOI:10.1016/s0169-328x(99)00311-3
PMID:10648902
Abstract

The localization of mRNA for SHIP2, SH2 domain containing inositol 5-phosphatase SHIP isozyme, was examined by in situ hybridization histochemistry in the brain of developing and mature rats. SHIP2 mRNA was first detected in the ventricular germinal zone at embryonic stages. As the postnatal development proceeded, the expression signal was evident in cell of the white matters, presumptive oligodendrocytes, and no significant expression was seen in neurons throughout the development.

摘要

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