Shabunin I V, Shimanovskiĭ N L, Panov V O, Kalinina A A, Sviridov N K
Department of Molecular Pharmacology and Radiobiology, Russian State Medical University, Moscow, Russia.
Eksp Klin Farmakol. 1999 Nov-Dec;62(6):62-5.
It was shown by the method of fluorescent probes that iodine-containing radiocontrast agents Triombrast > Omnipaque > Ultravist > Melitrast increase the content of intracellular Ca2+ in macrophages of the abdominal cavity of rats. Increase in the entry of Ca2+ from the external environment is the main factor of the change in the intracellular concentration of Ca2+ ions in the macrophages in interaction with radiocontrast agents.