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听神经瘤患者的正常听力学表现:使用严格听力学参数的评估

Normal audiologic presentations in patients with acoustic neuroma: An evaluation using strict audiologic parameters.

作者信息

Magdziarz D D, Wiet R J, Dinces E A, Adamiec L C

机构信息

Midwestern University/Chicago College of Osteopathic Medicine, Downers Grove, Illinois, USA.

出版信息

Otolaryngol Head Neck Surg. 2000 Feb;122(2):157-62. doi: 10.1016/S0194-5998(00)70232-4.

Abstract

Although several studies have previously reported on patients presenting with "normal" audiologic parameters in acoustic neuroma, the present study is, to our knowledge, the first to exclusively examine in detail cases involving exceptionally stringent objective audiometric features. Of 369 patients with acoustic neuroma who were operated on between April 1980 and April 1997 by our group, 10 had strictly normal hearing, defined as follows: (1) pure-tone average < 20 dB; (2) speech discrimination score > 90%; and (3) interaural differences </= 10 dB at every hertz level. A high level of audiologic functioning was found to significantly lower the sensitivity of auditory brainstem response in the detection of acoustic neuroma. Magnetic resonance imaging was the only preoperative test exhibiting 100% sensitivity in this setting. Thus, a high level of clinical suspicion appears warranted in any case involving unexplained unilateral audiovestibular symptoms-including those instances in which strictly normal hearing parameters exist and are associated with negative auditory brainstem response findings.

摘要

尽管此前已有多项研究报道了听力学参数“正常”的听神经瘤患者,但据我们所知,本研究是首次专门详细研究涉及异常严格客观听力特征的病例。在1980年4月至1997年4月期间由我们团队进行手术的369例听神经瘤患者中,有10例听力完全正常,定义如下:(1)纯音平均听阈<20dB;(2)言语识别率>90%;(3)每赫兹水平双耳差异≤10dB。发现高水平的听力学功能会显著降低听性脑干反应检测听神经瘤的敏感性。在这种情况下,磁共振成像(MRI)是唯一术前检查敏感性达100%的方法。因此,在任何涉及无法解释的单侧听觉前庭症状的病例中,包括那些听力参数严格正常且听性脑干反应结果为阴性的情况,都似乎有必要保持高度的临床怀疑。

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