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老年人糖尿病的临床与实验室特征

Clinical and laboratory profile of diabetes in elderly.

作者信息

Singh N P, Pugazhendhi V, Das A K, Prakash A, Agarwal S K

机构信息

Department of Medicine, Maulana Azad Medical College, New Delhi.

出版信息

J Indian Med Assoc. 1999 Apr;97(4):124-8.

Abstract

India is amidst a demographic transition showing an ageing trend. This will increase non-communicable diseases including diabetes which is already showing an increasing trend. With scanty literature existing on elderly diabetics (> 60 years of age), it was decided to study the clinico-laboratory and complication profile of this group of patients. Fifty consecutive elderly diabetics were studied and evaluated for ECG, chest x-ray, blood sugar, urea, creatinine, lipid profile, proteinuria, motor nerve conduction velocity and autonomic neuropathy. Duration of diabetes varied from one month to 28 years. Fifty-six per cent of the patients presented with classical symptoms of polyuria, polyphagia and polydipsia. Hypertension was present in 40% and cataract in 54% of the patients. Eighteen per cent were obese, 52% had evidence of peripheral neuropathy while 56% had autonomic neuropathy. Background diabetic retinopathy was present in 56%, pre-proliferative retinopathy and maculopathy in 4% each; hypertensive retinopathy in 10% of patients; 44% had microproteinuria and 8% had chronic renal failure. Hypercholesterolaemia was present in 64% and hypertriglyceridaemia in 42% of the patients with 26% having coronary artery disease. Sixty per cent were harbouring infections--20% had foot infections, 14% had tuberculosis and 10% had urinary tract infections. Ninety-two per cent of the patients were aware of their disease but 62% were not aware of the complications and of the need for strict dietary and drug compliance. There was a high prevalence of associated diseases viz, osteoarthritis, cataract, hypertension, hepatitis and parkinsonism. Therefore, this study brings out the need to have a holistic and multidisciplinary approach for management of elderly diabetics who constitute a heterogeneous group with distinct health care problems.

摘要

印度正处于人口结构转变阶段,呈现出老龄化趋势。这将增加包括糖尿病在内的非传染性疾病,而糖尿病已经呈上升趋势。鉴于关于老年糖尿病患者(60岁以上)的文献稀少,因此决定研究这组患者的临床实验室检查结果及并发症情况。对50例连续的老年糖尿病患者进行了研究,并对其进行了心电图、胸部X光、血糖、尿素、肌酐、血脂谱、蛋白尿、运动神经传导速度和自主神经病变的评估。糖尿病病程从1个月到28年不等。56%的患者出现了多尿、多食和多饮的典型症状。40%的患者患有高血压,54%的患者患有白内障。18%的患者肥胖,52%有周围神经病变的迹象,56%有自主神经病变。56%的患者有背景性糖尿病视网膜病变,4%的患者有增殖前期视网膜病变和黄斑病变;10%的患者有高血压性视网膜病变;44%的患者有微量蛋白尿,8%的患者有慢性肾衰竭。64%的患者有高胆固醇血症,42%的患者有高甘油三酯血症,26%的患者有冠状动脉疾病。60%的患者有感染——20%有足部感染,14%有结核病,1

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