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年龄能否作为结直肠癌腹腔镜结肠切除术的一个指征?

Could age be an indication for laparoscopic colectomy in colorectal cancer?

作者信息

Delgado S, Lacy A M, García Valdecasas J C, Balagué C, Pera M, Salvador L, Momblan D, Visa J

机构信息

Department of Gastrointestinal Surgery, Institute of Digestive Diseases, Hospital Clinic, University of Barcelona, Spain.

出版信息

Surg Endosc. 2000 Jan;14(1):22-6. doi: 10.1007/s004649900004.

DOI:10.1007/s004649900004
PMID:10653230
Abstract

BACKGROUND

The incidence of colorectal carcinoma increases in the elderly. Regardless of age as an isolated factor, postoperative complications represent the main factor in increasing hospital mortality.

METHODS

The aim of this study was to compare the short-term results (first 30 postoperative days) after laparoscopically assisted colectomy (LAC) and open segmental colectomy (OC) in colorectal carcinoma between two groups of patients, older than 70 and younger than 70 years of age. In the study from November 1993 to June 1998, 255 patients were evaluated to participate.

RESULTS

Peristalsis, oral intake, and discharge from the hospital occurred earlier in LAC than in OC treated patients, in the two age groups. The mean operative time was significantly longer in the LAC than in the OC patients in the two age groups. No differences were observed in morbidity between LAC and OC in the group younger than 70 years of age. However, the overall morbidity was significantly lower in the LAC group in patients older than 70 years. One patient in the LAC group older than 70 years died.

CONCLUSION

These results suggest that laparoscopically assisted colectomy may be particularly indicated in elderly patients.

摘要

背景

结直肠癌的发病率在老年人中呈上升趋势。无论年龄作为一个独立因素如何,术后并发症都是导致医院死亡率上升的主要因素。

方法

本研究的目的是比较两组年龄大于70岁和小于70岁的结直肠癌患者行腹腔镜辅助结肠切除术(LAC)和开放节段性结肠切除术(OC)后的短期结果(术后前30天)。在1993年11月至1998年6月的研究中,对255例患者进行了评估以参与研究。

结果

在两个年龄组中,LAC治疗的患者肠蠕动、经口进食和出院时间均早于OC治疗的患者。两个年龄组中,LAC患者的平均手术时间均显著长于OC患者。70岁以下组中,LAC和OC的发病率无差异。然而,70岁以上患者中,LAC组的总体发病率显著较低。70岁以上LAC组中有1例患者死亡。

结论

这些结果表明,腹腔镜辅助结肠切除术可能特别适用于老年患者。

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