Goradia V K, Rochat M C, Kida M, Grana W A
Department of Orthopaedic Surgery and Rehabilitation, University of Oklahoma, Oklahoma City, USA.
Am J Sports Med. 2000 Jan-Feb;28(1):40-6. doi: 10.1177/03635465000280011901.
The purpose of this study was to describe the histologic structure of the intraarticular segment of a semitendinosus tendon autograft used for anterior cruciate ligament reconstruction over the first year after surgery. We performed an anterior cruciate ligament reconstruction in a single hindlimb of 11 sheep using a doubled semitendinosus tendon autograft secured to the femur with an endoscopic button and polyester tape and to the tibia with sutures tied around a screw. The histologic structure of the intraarticular segment of the graft at 4, 8, 12, 24, and 52 weeks after surgery was compared with that of the normal semitendinosus tendon and anterior cruciate ligament. The random collagen fiber orientation progressed to a longitudinal orientation from the peripheral to the central areas of the graft over the initial 12 weeks after surgery. A uniform sinusoidal crimp pattern similar to that seen in the normal anterior cruciate ligament was identified under polarized light in nearly one-half of each graft by 24 weeks. Further maturation was noted at 52 weeks. Graft necrosis was not evident at any time period. This study showed that semitendinosus tendon autografts transform into a histologic structure similar to that of the normal anterior cruciate ligament over the initial year after surgery, as has been described for patellar tendon grafts.
本研究的目的是描述用于前交叉韧带重建的半腱肌肌腱自体移植物在术后第一年关节内段的组织学结构。我们使用双股半腱肌肌腱自体移植物对11只绵羊的单个后肢进行前交叉韧带重建，该移植物通过内镜纽扣和聚酯带固定于股骨，通过围绕螺钉打结的缝线固定于胫骨。将术后4周、8周、12周、24周和52周时移植物关节内段的组织学结构与正常半腱肌肌腱和前交叉韧带的组织学结构进行比较。术后最初12周内，移植物外周至中央区域的随机胶原纤维方向逐渐转变为纵向方向。到24周时，在偏振光下，几乎每个移植物的近一半区域可观察到与正常前交叉韧带相似的均匀正弦卷曲模式。52周时可见进一步成熟。在任何时间段均未发现移植物坏死。本研究表明，与髌腱移植物的情况类似，半腱肌肌腱自体移植物在术后最初一年内会转变为与正常前交叉韧带相似的组织学结构。
