Wang I C, Guo J X, Ma Y X, Chung W C, Lu S C, Fan P C
Institute and Department of Parasitology, National Yangming University, Taipei, Taiwan, Republic of China.
J Helminthol. 1999 Dec;73(4):347-50.
In order to determine whether Taenia solium can be maintained in the laboratory using rodents as definitive hosts, six nude rats, 20 immunosuppressed Mongolian gerbils and 20 immunosuppressed Syrian hamsters were each inoculated through a stomach tube with three cysticerci recovered from SCID mice. No adult worms of T. solium were found in the intestinal tract of any of these 46 rodents. In addition, five immunosuppressed Syrian hamsters were fed with the same number of cysticerci enclosed in rodent muscles from SCID mice. Two of these hamsters were found to be infected 40 days post-infection, each harbouring a sexually developed worm in the intestinal tract. Although no eggs were produced, prepatent infections may be possible if a longer time was allowed for worm development. Moreover, the maintenance of the life cycle of T. solium in the laboratory using the rodent model can be established.
为了确定是否可以在实验室中使用啮齿动物作为终宿主来维持猪带绦虫的生存，给6只裸鼠、20只免疫抑制的蒙古沙鼠和20只免疫抑制的叙利亚仓鼠分别经胃管接种从SCID小鼠中获得的3个囊尾蚴。在这46只啮齿动物的肠道中均未发现猪带绦虫成虫。此外，给5只免疫抑制的叙利亚仓鼠喂食来自SCID小鼠的包裹在啮齿动物肌肉中的相同数量的囊尾蚴。感染后40天发现其中2只仓鼠被感染，每只在肠道中都有一条性成熟的虫体。虽然没有产出虫卵，但如果给予更长的时间让虫体发育，可能会出现潜伏期感染。此外，可以在实验室中使用啮齿动物模型建立猪带绦虫的生命周期维持。
